Two Republican candidates for state Assembly seats on Manhattan’s East side will run on the “Stop de Blasio” ballot line newly and successfully created by political activists, the Manhattan GOP chair announced Monday.

The ballot line, as promoted in a news release from local Republican officials, misspells the name of New York City’s Mayor Bill de Blasio and aims to rally opponents of the Democratic mayor. It was approved on Friday.

Manhattan GOP chair Adele Malpass said in a statement that 1,500 registered voter signatures were collected to create the ballot position, which “will create a timely opportunity for voters to send a message prior to the 2017 municipal elections.”

De Blasio is up for re-election in 2017. A Quinnipiac University poll that surveyed voters in late July found 51 percent disapprove of his performance as mayor.

Dan Levitan, a de Blasio spokesman, said in response to the new ballot line cited the city’s low crime and high job creation rates as well as improving housing options and test scores.

“New Yorkers are interested in results, not gimmicks,” Levitan said, adding of candidates campaigning to stop de Blasio, “If they want to run against success, good luck to them, but they might do better with ideas of their own about improving New York.”

GOP Assembly candidates Rebecca Harary and Jon Kostakopoulos will run on the “Stop de Blasio” line as well as the Republican line, Malpass said.