Thousands of fans head to New York Comic Con each year to hear from the actors and creators behind their favorite shows, books and movies.

Rosario Dawson, Kevin Smith, Neil deGrasse Tyson and Keanu Reeves were among the luminaries to help kick off Comic Con's run at the Javits Center and at other venues around Manhattan. Several other celebs, including "The Walking Dead" cast members, made appearances throughout the weekend.

The pop culture event ran through Oct. 8. Here's a look at some of the famous guests.

William Shatner

William Shatner speaks at the world premiere of
William Shatner speaks at the world premiere of "Batman vs. Two Face" at New York Comic Con on Sunday, Oct. 8, 2017. (Credit: Getty Images / Dia Dipasupil )

Gillian Anderson and David Duchovny

Gillian Anderson and David Duchovny speak at an
Gillian Anderson and David Duchovny speak at an "X-Files" panel at New York Comic-Con on Sunday, Oct. 8, 2017. (Credit: Getty Images / Dia Dipasupil )

John Krasinski

John Krasinski discusses Tom Clancy's
John Krasinski discusses Tom Clancy's "Jack Ryan" onstage during New York Comic Con at the Javits Center in Manhattan on Saturday, Oct. 7, 2017. (Credit: AFP / Getty Images / Angela Weiss)

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Carlton Cuse, John Krasinski, Abbie Cornish, Terri Schwartz

Carlton Cuse, John Krasinski, Abbie Cornish and Terri
Carlton Cuse, John Krasinski, Abbie Cornish and Terri Schwartz discuss Tom Clancy's "Jack Ryan" onstage during New York Comic Con at the Javits Center in Manhattan on Saturday, Oct. 7, 2017. (Credit: AFP / Getty Images / Angela Weiss)

'The Walking Dead' cast

Norman Reedus, far left, Gale Ann Hurd, Chris
Norman Reedus, far left, Gale Ann Hurd, Chris Hardwick, Greg Nicotero, David Alpert, Robert Kirkman, Melissa McBride, Katelyn Nacon, Tom Payne, Lennie James, Andrew Lincoln, Jeffrey Dean Morgan and Austin Amelio pose for a selfie during the New York Comic Con "The Walking Dead" panel at The Theater at Madison Square Garden in Manhattan on Saturday, Oct. 7, 2017. (Credit: Getty Images for AMC / Jamie McCarthy)

Casey Willis, Aisha Tyler, Amber Nash, Lucky Yates and Matt Thompson

Casey Willis, Aisha Tyler, Amber Nash, Lucky Yates
Casey Willis, Aisha Tyler, Amber Nash, Lucky Yates and Matt Thompson attend the "Archer: Danger Island" Screening and Q&A panel during New York Comic Con at the Hammerstein Ballroom in Manhattan on Saturday, Oct. 7, 2017. (Credit: Getty Images / Nicholas Hunt)

'Dirk Gently's Holistic Detective Agency' cast

From left to right: Samuel Barnett, Fiona Dourif,
From left to right: Samuel Barnett, Fiona Dourif, Jade Eshete, Hannah Marks, Mpho Koaho, Max Landis and Elijah Wood pose onstage at the "Dirk Gently's Holistic Detective Agency" - BBC AMERICA panel during New York Comic Con at the Jacob K. Javits Convention Center on Oct. 6, 2017. (Credit: Getty Images / Nicholas Hunt)

Josh Hutcherson, Haley Joel Osment and Derek Wilson

Josh Hutcherson, Haley Joel Osment and Derek Wilson
Josh Hutcherson, Haley Joel Osment and Derek Wilson participate in Hulu's "Future Man" panel during New York Comic Con at the Jacob K. Javits Convention Center in Manhattan on Oct. 6, 2017. (Credit: Getty Images for Hulu / Mike Coppola)

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Macaulay Culkin and more from 'Robot Chicken'

Keith Crofford, Seth Green, Matt Senreich, Breckin Meyer,
Keith Crofford, Seth Green, Matt Senreich, Breckin Meyer, Clare Grant, Macaulay Culkin, Tom Root and Tom Sheppard pose onstage at the "Robot Chicken" panel during New York Comic Con at Hammerstein Ballroom in Manhattan on Oct. 6, 2017. (Credit: Getty Images for Adult Swim / Jason Kempin)

Macaulay Culkin

Macaulay Culkin speaks onstage at the
Macaulay Culkin speaks onstage at the "Robot Chicken" panel during New York Comic Con at the Hammerstein Ballroom in Manhattan on Oct. 6, 2017. (Credit: Getty Images for Adult Swim / Jason Kempin)

Rosario Dawson

Rosario Dawson speaks at the Audible Presents:
Rosario Dawson speaks at the Audible Presents: "Artemis" panel at the Javits Center on Oct. 5, 2017. (Credit: AFP/Getty Images / Angela Weiss)

Kevin Smith

Kevin Smith speaks during the Comic Book Men
Kevin Smith speaks during the Comic Book Men panel at the Hammerstein Ballroom in Manhattan on Oct. 5, 2017. (Credit: Getty Images / Cindy Ord)

Neil deGrasse Tyson, Chuck Nice and Adam Savage

Chuck Nice, Adam Savage and Neil deGrasse Tyson
Chuck Nice, Adam Savage and Neil deGrasse Tyson during the StarTalk Radio panel at the Javits Center on Oct. 5, 2017. (Credit: Getty Images / Mike Coppola)

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Vivica A. Fox

Vivica A. Fox during the
Vivica A. Fox during the "Explosion Jones" panel at the Javits Center on Oct. 5, 2017. (Credit: AFP / Getty Images / Angela Weiss)

Keanu Reeves

Keanu Reeves discusses
Keanu Reeves discusses "Replicas" at the Javits Center on Oct. 5, 2017. (Credit: Getty Images / Dia Dipasupil)

John Leguizamo

John Leguizamo during the
John Leguizamo during the "Freak!" The Comic Book! panel at the Javits Center on Oct. 5, 2017. (Credit: Getty Images / Nicholas Hunt)

Melissa Joan Hart

Melissa Joan Hart, center, and her mother, Paula
Melissa Joan Hart, center, and her mother, Paula Hart, right attend Lifetime's "The Watcher In The Woods" panel at the Javits Center on Oct. 5, 2017. (Credit: Getty Images for Lifetime / Astrid Stawiarz)