After more than a century in business, De Robertis Pasticceria and Caffé, at E. 11th St. and First Ave., will close for good this Fri., Dec. 5. Taken together with the closing of Pasticceria Bruno on LaGuardia Place, it’s a perfect storm of pastry shop closings for Downtown Manhattan. A traditional, no-frills pastry shop, De Robertis first opened its doors in 1904, and was immortalized on screen in Woody Allen’s “Manhattan Murder Mystery,” Spike Lee’s “Malcolm X” and “Sex and the City.” John De Robertis, the grandson of the founder, said the decision to close was based on the remaining siblings’ health concerns and a change in consumer tastes. The family owns the building, which they are reportedly selling for $12 million.