The New York Giants hit the road seeking back-to-back victories for the first time since 2023 when they visit the Denver Broncos at Empower Field at Mile High on Sunday afternoon. The Giants dismantled the Philadelphia Eagles with a 34-17 win on Thursday Night Football in Week 6 to improve their record to 2-4. The Broncos bring a 4-2 record into Week 7 following a slim 13-11 win over the New York Jets in London, England on Sunday morning.
While the road trip won’t be an easy matchup for New York, quarterback Jaxson Dart and running back Cam Skattebo will be riding high after excellent performances against the defending Super Bowl Champions from Philly. Will the duo be able to produce enough yardage in the crisp, mile-high air to lead the Giants to another win?
Week 7: New York Giants (2-4) @ Denver Broncos (4-2)
Kick Off: 4:05 p.m. ET (Sun., 10/19/25)
Location: Empower Field at Mile High (Denver, Colorado)
The Broncos open as slightly more than touchdown favorite at home against Big Blue in Week 7. Denver holds a 3-3 record against the spread, while New York is 2-4 this season. The Giants have paid out money line bets four times with a 4-2 record against the money line, while Denver features an inverse record at 2-4. Neither team has been successful hitting the over/under line with the Broncos at 2-4 and the Giants at 1-5 in 2025.
| Spread | DEN -7.5 |
| Money Line | NYG +295, DEN -370 |
| Over/ Under Total | 40.5 Points |
| Money Against the Spread | 100% DEN |
| Bets Against the Spread | 83% DEN |
| Odds via FanDuel Sportsbook | Odds are subject to change |
ESPN Analytics projects Denver as a strong favorite with a 67% chance to win on Sunday.
Best Bet: Cam Skattebo 80+ Rushing Yards
Skattebo dashed for 98 yards and three touchdowns on 19 carries against Philadelphia on Thursday night. The Giants rookie also added two catches for 12 yards to push his overall performance above the 100+ yard threshold for the evening, the third time the RB has reached the combined rushing + receiving century mark this season. While most of the attention is being paid to his QB counterpart (Dart), Skattebo’s hard-nosed running is making most teams (and NFL fans) take notice. The time he’s been limited in running the football, the 23-year-old Arizona State product has found success receiving the football, including a six catch, 61-yard performance against the Kansas City Chiefs in Week 2.
Skattebo Rushing Yard Odds vs. Broncos in Week 7
| Skattebo 50+ Rushing Yards | -154 |
| Skattebo 70+ Rushing Yards | +182 |
| Skattebo 80+ Rushing Yards | +280 |
| Skattebo 100+ Rushing Yards | +580 |
| Odds via FanDuel Sportsbook | Odds are subject to change |
Denver brings a stout run defense into the matchup against New York with the 6th-best run-stopping group in the league. Opponents have scored only two rushing touchdowns against the Broncos in 2025, so expecting multiple touchdowns to the Giants rookie again this week would be foolish. Skattebo has averaged nearly 70 rushing yards and a touchdown in each of his first five games in the NFL. Still, there should be an opportunity for the Giants rookie to run the football against Denver in Week 7.
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